Effect of chronic obstructive pulmonary disease on cardiac function in patients with coronary heart disease

Objective To evaluate the effect of chronic obstructive pulmonary disease(COPD) on cardiac function in patients with coronary heart disease(CHD),and analyze the possible mechanisms.Methods The clinical data of 178 patients of CHD in our hospital from January 2011 to February 2012 were reviewed,including 96 patients complicated with COPD(group A),82 patients not complicated with COPD(group B).The complications,blood lipid levels and echocardiography results were analyzed.Results There was no statistically significant difference between the two groups in left atrial diameter,interventricular septal thickness,and diastolic diameter of left ventricle,posterior wall thickness of left ventricular,cardiac output and the width of the main pulmonary artery(P0.05).The inner diameter of the aortic sinus,right ventricular diastolic diameter and heart rate was increased significantly in group A compared with group B(P0.05),but left ventricular end-systolic volume,end-diastolic volume,left ventricular ejection fraction were significantly decreased(P0.002).Conclusion The study shows COPD can increase ventricular volume and decrease the ejection fraction in patients with CHD.