2014Pharmacy TodayRequires access

Quality Standard of Xianglianliqi Pills

Zhang Xueyua

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Abstract

Objective To establish the quality standard of Xianglianliqi pills. Methods Cortex Magnoliae Officenalis and Herba Pogostemonis and Radix et Rhizoma Glycyrrhizae in Xianglianliqi pills was identified by microscope. Rhizoma Coptidis,Radix Aucklandiae,Cortex Magnoliae Officenalis in Xianglianliqi pills was identified by TLC. HPLC was applied to determine the content of Magnolol and Honokiol in Xianglianliqi pills. Results: The 3 natural drugs could be identified by the established standard with high specificity. Honokiol showed a good liner relationship in the range of 6. 152- 92. 28μg/mL. The average recovery was 98. 95%( RSD = 0. 9%,n = 9). Magnolol showed a good liner relationship in the range of 8. 867- 133. 01 μg /mL. The average recovery was 99. 30%( RSD = 1. 2%,n = 9). Conclusion The quality standard is easy,user- friendly,accurate,and reproducible,which can be used for the quality control of Xianglianliqi pills.

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Objective To establish the quality standard of Xianglianliqi pills. Methods Cortex Magnoliae Officenalis and Herba Pogostemonis and Radix et Rhizoma Glycyrrhizae in Xianglianliqi pills was identified by microscope. Rhizoma Coptidis,Radix Aucklandiae,Cortex Magnoliae Officenalis in Xianglianliqi pills was identified by TLC. HPLC was applied to determine the content of Magnolol and Honokiol in Xianglianliqi pills. Results: The 3 natural drugs could be identified by the established standard with high specificity. Honokiol showed a good liner relationship in the range of 6. 152- 92. 28μg/mL. The average recovery was 98. 95%( RSD = 0. 9%,n = 9). Magnolol showed a good liner relationship in the range of 8. 867- 133. 01 μg /mL. The average recovery was 99. 30%( RSD = 1. 2%,n = 9). Conclusion The quality standard is easy,user- friendly,accurate,and reproducible,which can be used for the quality control of Xianglianliqi pills.

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Available abstract

Objective To establish the quality standard of Xianglianliqi pills. Methods Cortex Magnoliae Officenalis and Herba Pogostemonis and Radix et Rhizoma Glycyrrhizae in Xianglianliqi pills was identified by microscope. Rhizoma Coptidis,Radix Aucklandiae,Cortex Magnoliae Officenalis in Xianglianliqi pills was identified by TLC. HPLC was applied to determine the content of Magnolol and Honokiol in Xianglianliqi pills. Results: The 3 natural drugs could be identified by the established standard with high specificity. Honokiol showed a good liner relationship in the range of 6. 152- 92. 28μg/mL. The average recovery was 98. 95%( RSD = 0. 9%,n = 9). Magnolol showed a good liner relationship in the range of 8. 867- 133. 01 μg /mL. The average recovery was 99. 30%( RSD = 1. 2%,n = 9). Conclusion The quality standard is easy,user- friendly,accurate,and reproducible,which can be used for the quality control of Xianglianliqi pills.

Key concepts: Magnolol, Radix (gastropod), Honokiol, Pill, Quality standard, Traditional medicine, Chromatography, Medicine

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