Clinical observation of Silver-zinc Cream in treatment of degree II burn with contamination wounds

Objective To explore the efficacy of Silver-zinc Cream in the treatment of degree II burn with contamination wounds. Methods The patients suffered form degree II burn(102 cases) in No.3 People Hospital Affiliated to Shanghai Jiaotong University School of Medicine from March 2011 to February 2014 were randomly divided into treatment and control groups,and there were 51 cases in each group. All the patients were given debridement and wound cleaning processing,and were given regular rehydration and analgesic treatment. The patients in the treatment group used Silver-zinc Cream for external coating treatment,once daily; The patients in the control group used Moist Burn Cream for external coating treatment,3 times daily. The drugs were applied right amount thickness in the treatment of wound by bandaged and the drug usage time was decided according to the condition of patients. Switching frequency,time of healing,antibiotic usage,hospital stay,and situation of wound healing were compared. ResultsSwitching frequency,time of healing,antibiotic usage,hospital stay,and situation of wound healing in the treatment group are significantly shorter than those in the control group,with the significant difference between the two groups(P 0.05). Burn wound healing rate was significant difference between the two groups(P 0.05). Burn wound healing rate of shallow degree II and deep degree II in the treatment group for 4 d,1 week,and 2 weeks after the treatment were significantly higher than those in the control group,with the significant difference between the two groups(P 0.05). Adverse events of wound deepened,sepsis,and wound odor were happened in the two groups. Incidence of wound odor in the treatment group was obviously lower than that in the control group,with the significant difference between the two groups(P 0.05). There was no fever in the treatment group,while the incidence of fever in the control group was 7.84%,with the significant difference between the two groups(P 0.05). Conclusion Silver-zinc Cream has a good clinical efficacy in the treatment of degree II burn with contamination wounds,and could obviously improve the condition of wound healing,which is worthy of clinical application.