ScholarLens Back to search
2007•Zhongguo shengwuzhipinxue zazhiRequires access

Immune Effect of Hepatitis A and B Combined Vaccine in Adults without Response to Hepatitis B Vaccine

Qing Cao

Open publisher page 0 citations

Abstract

Objective To explore the immune strategy of hepatitis B vaccine in adults.Methods Inoculate hepatitis A and B combined vaccine by a schedule of 0,1,6 months,each at a dosage of 20 μg,to 228 adults without response to several doses of hepatitis B vaccine.Collect serum sample 1 month after the third dose of combined vaccine was given for determination of anti-HBs by radioimmunoassay.Results The anti-HBs were positive in 172(75.44%) of 228 adult subjects,and the GMT of anti-HBs was 197.20 mIU/ml.Conclusion Hepatitis A and B combined vaccine enhanced the positive conversion of anti-HBs in adults without response to several doses of hepatitis B vaccine.

About this research paper

What this paper is about

Objective To explore the immune strategy of hepatitis B vaccine in adults.Methods Inoculate hepatitis A and B combined vaccine by a schedule of 0,1,6 months,each at a dosage of 20 μg,to 228 adults without response to several doses of hepatitis B vaccine.Collect serum sample 1 month after the third dose of combined vaccine was given for determination of anti-HBs by radioimmunoassay.Results The anti-HBs were positive in 172(75.44%) of 228 adult subjects,and the GMT of anti-HBs was 197.20 mIU/ml.Conclusion Hepatitis A and B combined vaccine enhanced the positive conversion of anti-HBs in adults without response to several doses of hepatitis B vaccine.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To explore the immune strategy of hepatitis B vaccine in adults.Methods Inoculate hepatitis A and B combined vaccine by a schedule of 0,1,6 months,each at a dosage of 20 μg,to 228 adults without response to several doses of hepatitis B vaccine.Collect serum sample 1 month after the third dose of combined vaccine was given for determination of anti-HBs by radioimmunoassay.Results The anti-HBs were positive in 172(75.44%) of 228 adult subjects,and the GMT of anti-HBs was 197.20 mIU/ml.Conclusion Hepatitis A and B combined vaccine enhanced the positive conversion of anti-HBs in adults without response to several doses of hepatitis B vaccine.

Key concepts: Hepatitis B vaccine, Medicine, Hepatitis A vaccine, Hepatitis B, Immune system, Vaccination schedule, Immunology, Radioimmunoassay

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Immune Effect of Hepatitis A and B Combined Vaccine in Adults without Response to Hepatitis B Vaccine — Research Paper | ScholarLens