Separation and drug resistance analysis of Pseudomonas aeruginosa

Objective To investigate the present consent condition of infection,feature of distribution and resistance of the Pseudomonas aeruginosa,and to guide our rational drug administration in clinical practice.Methods One thousand one hundred and ninety-five plants of the Pseudomonas aeruginosa were collected from January 2007 to December 2009.A statistic analysis for the specimen source,departments with infection and drug resistance condition were analyzed by retrospective method.Results One thousand one hundred and ninety-five plants of the Pseudomonas aeruginosa were detected in total.79.4% came from sputum and throat mucus,9.5% came from urine,and 3.6% came from blood.46.7% came from respiratory medicine,20.8% came from intensive care unit,and 7.9% came from surgical in the distribution of lesion.There were statistically significant in the resistance rates of Pseudomonas aeruginosa to ciprofloxacin,gentamicin,piperacillin and piperacillin / tazobactam among three years(P0.05).Resistance rates of Pseudomonas aeruginosa to imipenem and ceftazidime were increasing trend year by year,and the resistance rates of Pseudomonas aeruginosa to meropenem and ticarcillin / clavulanic acid were a declining trend year by year,but there was no statistically significant(P0.05).Conclusion Clinical isolates of Pseudomonas aeruginosa come from the sputum and throat mucus and respiratory department mainly.Timely identifying bacteria and perfoming drug sensitivity tests may help find out nosocomial infection of Pseudomonas aeruginosa and thus provide important laboratory evidence for clinical treatment.