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Correlation analysis between level of TNF-α in gingival crevicular fluid and glycosylated hemoglobin in diabetes mellitus paticnt with periodonitis

Xue Li

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Abstract

AIM:To investigate the level of tumor necrosis factor-alpha(TNF-α)in gingival crevicular fluid(GCF)from insulin dependent diabetes mellitus paticnt with periodontitis,simplex periodontitis and periodontal health person,and the relationship between TNF-α concentration and metabolic condition.METHODS:The level of TNF-α in GCF was measured by ELISA.The concentration of HbA1c in IDDM patients was analyzed.RESULTS:The level of TNF-α in GCF from insulin dependent diabetes mellitus paticnt with periodontitis was significantly higher than that from simplex periodontitis and the control group.The level of TNF-α in GCF was irrelevant to HbA1c was irrelevaht.CONCLUSION:Diabetes can promote the level of TNF-α in GCF from periodontitis.

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What this paper is about

AIM:To investigate the level of tumor necrosis factor-alpha(TNF-α)in gingival crevicular fluid(GCF)from insulin dependent diabetes mellitus paticnt with periodontitis,simplex periodontitis and periodontal health person,and the relationship between TNF-α concentration and metabolic condition.METHODS:The level of TNF-α in GCF was measured by ELISA.The concentration of HbA1c in IDDM patients was analyzed.RESULTS:The level of TNF-α in GCF from insulin dependent diabetes mellitus paticnt with periodontitis was significantly higher than that from simplex periodontitis and the control group.The level of TNF-α in GCF was irrelevant to HbA1c was irrelevaht.CONCLUSION:Diabetes can promote the level of TNF-α in GCF from periodontitis.

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Available abstract

AIM:To investigate the level of tumor necrosis factor-alpha(TNF-α)in gingival crevicular fluid(GCF)from insulin dependent diabetes mellitus paticnt with periodontitis,simplex periodontitis and periodontal health person,and the relationship between TNF-α concentration and metabolic condition.METHODS:The level of TNF-α in GCF was measured by ELISA.The concentration of HbA1c in IDDM patients was analyzed.RESULTS:The level of TNF-α in GCF from insulin dependent diabetes mellitus paticnt with periodontitis was significantly higher than that from simplex periodontitis and the control group.The level of TNF-α in GCF was irrelevant to HbA1c was irrelevaht.CONCLUSION:Diabetes can promote the level of TNF-α in GCF from periodontitis.

Key concepts: Periodontitis, Medicine, Diabetes mellitus, Internal medicine, Hemoglobin, Tumor necrosis factor alpha, Chronic periodontitis, Gastroenterology

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Correlation analysis between level of TNF-α in gingival crevicular fluid and glycosylated hemoglobin in diabetes mellitus paticnt with periodonitis — Research Paper | ScholarLens