2012•Chemical Research and ApplicationRequires access

Research progress of β-cyclodextrin bonded stationary phases and chiral separation in HPLC

Wei Guo

Abstract

β-Cyclodextrin was a cyclic oligosaccharide,which was connected end to end by 1,4-glycosidic bond.It had the function of chiral recognition.Especially the derivative β-cyclodextrin bonded liquid chromatography stationary phases had good chiral separation ability to chiral compounds.In this paper,the structure and properties of β-cyclodextrin were introduced and all kinds of derivative β-cyclodextrins bonded liquid chromatography stationary phases and its application in chiral separation were summarized.

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Available abstract

Key concepts: Cyclodextrin, Glycosidic bond, High-performance liquid chromatography, Chiral column chromatography, Chromatography, Chemistry, Derivative (finance), Chirality (physics)