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Trend in application of β-cyclodextrin bonded stationary phases for chiral separation in chromatography

Ji Zhang

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Abstract

Due to its optical activity,βcyclodextrin (βCD) has the ability of chiral recognition to guest molecules.Therefore,βCDs are extensively used as stationary phases in chromatography.A review on the new utilizations and the tendency of the development of βCD bonded stationary phases for chiral separation in chromatography was given,with 34 references.We also summarized the new views on the chiral recognition mechanism.

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What this paper is about

Due to its optical activity,βcyclodextrin (βCD) has the ability of chiral recognition to guest molecules.Therefore,βCDs are extensively used as stationary phases in chromatography.A review on the new utilizations and the tendency of the development of βCD bonded stationary phases for chiral separation in chromatography was given,with 34 references.We also summarized the new views on the chiral recognition mechanism.

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Available abstract

Due to its optical activity,βcyclodextrin (βCD) has the ability of chiral recognition to guest molecules.Therefore,βCDs are extensively used as stationary phases in chromatography.A review on the new utilizations and the tendency of the development of βCD bonded stationary phases for chiral separation in chromatography was given,with 34 references.We also summarized the new views on the chiral recognition mechanism.

Key concepts: Cyclodextrin, Stationary phase, Chromatography, Chemistry, Molecule, Chiral column chromatography, Mechanism (biology), Chiral stationary phase

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