Advances in Gene Therapy: Adeno-Associated Virus (AAV) Vectors
He Chengwei
Abstract
He Chengwei
Abstract
Adeno-associated virus (AAV) vectors show great promise for gene therapy.The extensive application of this vector system in the basic medical sciences and clinical practice, however, is limited by their biological properties.This study explored the possibilities of expanding their use by introducing new techniques of packaging, production, purification and speeding-limiting method in AAV transduction.
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Adeno-associated virus (AAV) vectors show great promise for gene therapy.The extensive application of this vector system in the basic medical sciences and clinical practice, however, is limited by their biological properties.This study explored the possibilities of expanding their use by introducing new techniques of packaging, production, purification and speeding-limiting method in AAV transduction.
Key concepts: Adeno-associated virus, Transduction (biophysics), Genetic enhancement, Limiting, Vector (molecular biology), Gene transfer, Virology, Biology