2008•Applied Journal of General PracticeRequires access

Therapeutic Efficacy of Metoprolol in Patient with Chronic Heart Failure

Xingyan Li

Abstract

Objective To observe the efficacy and safety of metoprolol for the patients with chronic heart failure(CHF).Methods One hundred and sixty patients with chronic heart failure were randomly assigned to control group(n=80) and treatment group(n=80).The control group received routine CHF treatment while the treatment group received additionally metoprolol.The development of CHF was observed for 18 months.Results There were a significant improvement in echocardiography,24h dynamic ECG and the distance for 6 minutes walking test in the treated group as compared with the comparative group(P0.05).The rate of rehospitalization and mortality rate were lower markedly than that in the control group(P0.01).Conclusions Metoprolol is a medicine of high efficacy on the chronic heart failure.

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Key concepts: Metoprolol, Medicine, Heart failure, Internal medicine, Cardiology, Treatment and control groups, Anesthesia