Values of Detection of Serum Cystatin C,Urine Micro-albumin,Urine β_2-Microglobin in Patients with Liver Cirrhosis
Yan Zhang
Abstract
Yan Zhang
Abstract
Objective To explore the values of serum cystatin C(Cys-C),Urine Microalbuminand(UMAlb) and Urine β_2- Microglobin(β_2-MG) in Patients with liver cirrhosis.Methods The Serum Cys-C,umAlb(with immunoturbility assay) and Uβ_2-MG(with ELISA) Levels were determined in 61 patients with liver cirrhosis(30 cases ascites the cirrhosis and 31 cases without ascites) and 35 healthy controls.Results The Serum Cys- C and UmAlb and β_2-MG levels in patients were significantly higher than those in controls(P 0.01).These markers in liver cirrhosis with ascites group were higher that that without ascites groups(P 0.01).Theserum Cys-C levels were positively correlated with UmAlb and Uβ_2-MG levels(r = 0.6011,0.5984,P 0.01).Conclusion The detection levels of serum Cys-C,UmALb and Uβ_2-MG have important value in the early diagnosing renal function damage.
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Objective To explore the values of serum cystatin C(Cys-C),Urine Microalbuminand(UMAlb) and Urine β_2- Microglobin(β_2-MG) in Patients with liver cirrhosis.Methods The Serum Cys-C,umAlb(with immunoturbility assay) and Uβ_2-MG(with ELISA) Levels were determined in 61 patients with liver cirrhosis(30 cases ascites the cirrhosis and 31 cases without ascites) and 35 healthy controls.Results The Serum Cys- C and UmAlb and β_2-MG levels in patients were significantly higher than those in controls(P 0.01).These markers in liver cirrhosis with ascites group were higher that that without ascites groups(P 0.01).Theserum Cys-C levels were positively correlated with UmAlb and Uβ_2-MG levels(r = 0.6011,0.5984,P 0.01).Conclusion The detection levels of serum Cys-C,UmALb and Uβ_2-MG have important value in the early diagnosing renal function damage.
Key concepts: Ascites, Cirrhosis, Medicine, Urine, Internal medicine, Cystatin C, Gastroenterology, Albumin