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2008•Zhongguo fuyou baojianRequires access

Expression and significance of estrogen,progesterone recepctor and proliferating cell nuclear antigen in uterine leiomyoma and their corresponding myometrium

Li Cui

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Abstract

Objective:To approach the developed mechanism of hysteromyoma.Methods:Immunohistochemical SP method was used to detect the expressions of estrogen receptor(ER),progesterone receptor(PR)and proliferating cell nuclear antigen(PCNA)in 30 examples of uterine leiomyoma and their corresponding myometrium.Results:The positive rates of the expressions of ER and PR in hysteromyoma were 70% and 63.33%,and those of their corresponding myometrium were 43.33% and 33.33% respectively(P0.05).The expression of PCNA in hysteromyoma was obviously stronger than that of its corresponding myometrium(P0.01).Conclusion:The genesis and development of hysteromyoma may be correlative with ER,PR and PCNA.

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What this paper is about

Objective:To approach the developed mechanism of hysteromyoma.Methods:Immunohistochemical SP method was used to detect the expressions of estrogen receptor(ER),progesterone receptor(PR)and proliferating cell nuclear antigen(PCNA)in 30 examples of uterine leiomyoma and their corresponding myometrium.Results:The positive rates of the expressions of ER and PR in hysteromyoma were 70% and 63.33%,and those of their corresponding myometrium were 43.33% and 33.33% respectively(P0.05).The expression of PCNA in hysteromyoma was obviously stronger than that of its corresponding myometrium(P0.01).Conclusion:The genesis and development of hysteromyoma may be correlative with ER,PR and PCNA.

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Available abstract

Objective:To approach the developed mechanism of hysteromyoma.Methods:Immunohistochemical SP method was used to detect the expressions of estrogen receptor(ER),progesterone receptor(PR)and proliferating cell nuclear antigen(PCNA)in 30 examples of uterine leiomyoma and their corresponding myometrium.Results:The positive rates of the expressions of ER and PR in hysteromyoma were 70% and 63.33%,and those of their corresponding myometrium were 43.33% and 33.33% respectively(P0.05).The expression of PCNA in hysteromyoma was obviously stronger than that of its corresponding myometrium(P0.01).Conclusion:The genesis and development of hysteromyoma may be correlative with ER,PR and PCNA.

Key concepts: Myometrium, Proliferating cell nuclear antigen, Progesterone receptor, Immunohistochemistry, Estrogen, Estrogen receptor, Leiomyoma, Medicine

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Expression and significance of estrogen,progesterone recepctor and proliferating cell nuclear antigen in uterine leiomyoma and their corresponding myometrium — Research Paper | ScholarLens