2015•Hainan Yixueyuan xuebaoRequires access
Effect of hemodialysis combined blood perfusion on micro inflammation and nutrition status of diabetic nephropathy patients
Xie Jin-li
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Abstract
Objective:To study the effect of hemodialysis combined blood perfusion on micro inflammation and nutrition status of diabetic nephropathy patients.Methods:A total of 118 cases of diabetic nephropathy received treatment in our hospital from December 2012 to December 2014 were selected for study and randomly divided into two group.Observation group received hemodialysis combined blood perfusion,control group received pure hemodialysis therapy.Then nutrition status index,biochemical index and inflammation response degree were compared.Results:Compared with control group,serum Hb and Alb levels of observation group showed increasing trend,MAC and MAMC showed ncreasing trend.Compared with control group,serum mRNA levels of IGF-1,PA,TRF,RBP of observation group showed increasing trend.Compared with control group,serum IL-17,IL-22,IL-1β,TGF-β1,SAA levels of observation group showed decreased trend.Conclusion:Hemodialysis combined blood perfusion treatment can effectively reduce inflammation in patients with diabetic nephropathy,and can improve general nutritional status.