2004•Chinese Journal of New Drugs and Clinical RemediesRequires access
A new antifungal agent voriconazole
Mingkang Zhong
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Abstract
Voriconazole is a second-generation azole antifungal agent that shows the characters of broad-spectrum and strong antibacterial, especially has good efficacy to the infection induced by invasive aspergillus. The oral formulation has excellent bioavailability and it is well tolerated. This paper reviews the progress in the pharmacodynamics, pharmacokinetics, drug-drug interactions and clinical application, adverse reactions of voriconazole.