The Detection and Analysis of Chlamydia trachomatis and Ureaplasma urealyticum of Gynecological Inflammation Disease

Objective To study the correlation of Chlamydia trachomatis(CT), Ureaplasma urealyticum(UU) infections and gynecological inflammation disease, and to investigate the pathological mechanism. Methods CT and UU were detected by fluorescence PCR technique in 820 swab specimens of gynecological inflammation disease in this study. Results In 458 cases of vaginits, the positive rate of CT was 10.26%, and UU was 65.94%. In 270 cases of cervicitis, the positive rate of CT was 11.85%, and UU was 60.00%. In 92 cases of pelvic inflammation, the positive rate of CT was 3.26%, and UU was 45.65%. 24 cases of vaginits, 13 cases of cervicitis and 1 cases of pelvic inflammation were infected with both CT and UU. There were significant differences between the positive rates of CT and UU among different groups(P0.01). There were no differences among different groups with the positive rates of CT or UU(P 0.05). Conclusion The results showed that the gynecological inflammation had a close relationship with the infections of CT and UU, and was likely due to the impaired immunity. The detection of CT and UU should be included in the clinical diagnosis of the gynecological inflammation disease.