2008•Food Science and Technology InternationalRequires access

Optimization of the extraction technology of oleanolic acid in radix scrophularfiae by orthogonal design

Hong San-guo

Abstract

Objective: To optimize the ultrasonic extraction condition for oleanolic acid from Radix Scrophularfiae.Method: UV was used to analyze the content of Oleanolic Acid.According to the orthogonal design L9(34),the optimization of the ultrasonic extraction technology was determined by test investigation and was compared with the routine extraction technique.Results: The optimum extraction condition was: 30 min(extracted 3 times)by ultrasonic extraction,80% ethanol solution,10 fold solvent.Conclusions: the optimized technology is quick,simple and accurate.It can be used for theoretical basis of Radix Scrophularfiae.

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Key concepts: Oleanolic acid, Extraction (chemistry), Radix (gastropod), Chromatography, Ultrasonic sensor, Solvent, Computer science, Process engineering