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Optimization of technology for extraction of chlorogenic acid from Flos Lonicerae with ethanol

Ran Xu

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Abstract

The optimum conditions for the extraction of chlorogenic acid from Flos Lonicerae with ethanol water as the solvent were studied.The effects of 4 factors(extraction temperature,extraction time,the ratio of material to solvent,ethanol concentration) on the extraction rate of chlorogenic acid were investigated.Through orthogonal experiments,the optimum conditions were determined as:extraction temperature 65℃,extraction time 20 min,the ratio of material to solvent 1∶15,and ethanol concentration 80%.Under such conditions,the extraction rate of chlorogenic acid reached 7.953%.It can be used as a valuable reference for the industrial production of chlorogenic acid.

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What this paper is about

The optimum conditions for the extraction of chlorogenic acid from Flos Lonicerae with ethanol water as the solvent were studied.The effects of 4 factors(extraction temperature,extraction time,the ratio of material to solvent,ethanol concentration) on the extraction rate of chlorogenic acid were investigated.Through orthogonal experiments,the optimum conditions were determined as:extraction temperature 65℃,extraction time 20 min,the ratio of material to solvent 1∶15,and ethanol concentration 80%.Under such conditions,the extraction rate of chlorogenic acid reached 7.953%.It can be used as a valuable reference for the industrial production of chlorogenic acid.

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Available abstract

The optimum conditions for the extraction of chlorogenic acid from Flos Lonicerae with ethanol water as the solvent were studied.The effects of 4 factors(extraction temperature,extraction time,the ratio of material to solvent,ethanol concentration) on the extraction rate of chlorogenic acid were investigated.Through orthogonal experiments,the optimum conditions were determined as:extraction temperature 65℃,extraction time 20 min,the ratio of material to solvent 1∶15,and ethanol concentration 80%.Under such conditions,the extraction rate of chlorogenic acid reached 7.953%.It can be used as a valuable reference for the industrial production of chlorogenic acid.

Key concepts: Chlorogenic acid, Flos, Extraction (chemistry), Chemistry, Chromatography, Solvent, Ethanol, Biochemistry

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