Optimization of technology for extraction of chlorogenic acid from Flos Lonicerae with ethanol
Ran Xu
Abstract
Ran Xu
Abstract
The optimum conditions for the extraction of chlorogenic acid from Flos Lonicerae with ethanol water as the solvent were studied.The effects of 4 factors(extraction temperature,extraction time,the ratio of material to solvent,ethanol concentration) on the extraction rate of chlorogenic acid were investigated.Through orthogonal experiments,the optimum conditions were determined as:extraction temperature 65℃,extraction time 20 min,the ratio of material to solvent 1∶15,and ethanol concentration 80%.Under such conditions,the extraction rate of chlorogenic acid reached 7.953%.It can be used as a valuable reference for the industrial production of chlorogenic acid.
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The optimum conditions for the extraction of chlorogenic acid from Flos Lonicerae with ethanol water as the solvent were studied.The effects of 4 factors(extraction temperature,extraction time,the ratio of material to solvent,ethanol concentration) on the extraction rate of chlorogenic acid were investigated.Through orthogonal experiments,the optimum conditions were determined as:extraction temperature 65℃,extraction time 20 min,the ratio of material to solvent 1∶15,and ethanol concentration 80%.Under such conditions,the extraction rate of chlorogenic acid reached 7.953%.It can be used as a valuable reference for the industrial production of chlorogenic acid.
Key concepts: Chlorogenic acid, Flos, Extraction (chemistry), Chemistry, Chromatography, Solvent, Ethanol, Biochemistry