Clinical research of CT-guided combined with injection of ozone and collagenase in the treatment of lumbar intervertebral disc herniation through inner margin of small joint

Objective:To discuss the clinical research of CT-guided combined with injection of ozone and collagenase in the treatment of lumbar intervertebral disc herniation through inner margin of small joint.Methods:All 45 patients with lumbar intervertebral disc herniation were injected 10ml of 60 μg/ml ozone under the guidence of CT.The needle punctures through the inner margin of diapophysis and gets in intervertebral disc.Then the needle is pulled back at lateral crypt fossa;5ml of 40μg/ml ozone and 600～1200u collagenase are injected.Results:Observing the location of ozone after operation and the therapy effect during 1～6 month.Evaluating therapy effect according to Macnab criteria,and the best,good,and poor therapy rate is 40%,53% and 7% respectively.Conclusion:Operation under CT-guidence is easy,safe and accurate.The therapy of injection of ozone in intervertebral disc and combined injection of ozone and collagenase in lateral crypt fossa is a minimally invasive and effective method.