To Evaluate the Results of Hepatitis B Vaccination Program in Zhongshan City

Objective To evaluate the hepatitis B vaccination program and find effective method to insure immunization quality. Method 2 495 healthy people were selected by radom-cluster-sampling method and assay for serum HBsAg/HBsAb by ELISA. Results HBsAb positive rate was 92.7% (141/152) in the group of newborn infants. HBsAb positive rate was 48.1% (1199/2495) and HBsAg positive rate was 10.4%(259/2496) in group over 1 year of age. HBsAg positive rate was 1.2% (10/844) in group from 1 to 18 years of age, and was 15.1% (249/1651) over 18 years of age. Conclusion The data suggests that vaccination against Hepatitis B timely and correctly of newborn infants could protect them against the disease. Improving the quantity and quality of immunization against Hepatitis B of the healthy people could increase the immunity against HBV and lower the infection rate of the high risk people. The low percentage of HBsAb positive rate in the infant of 1 year of age is a high risk of HBV infection in this population.