ScholarLens Back to search
2002•Journal of China Medical ImagingRequires access

Analysis of ECD/SPECT regional cerebral blood flow in anxiety disorder using statistical parametric mapping

Jiang Xu

Open publisher page 0 citations

Abstract

Objective:To analyze the regional cerebral blood flow(rCBF) alternations in patients with anxiety disorder,comparing with normal subjects using statistical parametric mapping.Methods:99mTc ECD-brain SPECT imaging were performed in 19 anxiety disorder patients(ADP) diagnosed with CCMD 2 or ICD 10,and 23 cases with age matched normal controls for comparison.Situation of rCBF in ADP was analyzed by SPM method under the condition of increased and decreased perfusion.Results:The rCBF of bilateral temporal,superior frontal gyrus and callosal gyrus were significantly decreased in the anxiety group,and the rCBF of precentral gyrus,frontal lobe orbital part,left basal ganglia was significantly increased(P0 05).Conclusion:SPM analysis showed that significant rCBF change in anxiety disorder patients and related to disease pathophysiology.

About this research paper

What this paper is about

Objective:To analyze the regional cerebral blood flow(rCBF) alternations in patients with anxiety disorder,comparing with normal subjects using statistical parametric mapping.Methods:99mTc ECD-brain SPECT imaging were performed in 19 anxiety disorder patients(ADP) diagnosed with CCMD 2 or ICD 10,and 23 cases with age matched normal controls for comparison.Situation of rCBF in ADP was analyzed by SPM method under the condition of increased and decreased perfusion.Results:The rCBF of bilateral temporal,superior frontal gyrus and callosal gyrus were significantly decreased in the anxiety group,and the rCBF of precentral gyrus,frontal lobe orbital part,left basal ganglia was significantly increased(P0 05).Conclusion:SPM analysis showed that significant rCBF change in anxiety disorder patients and related to disease pathophysiology.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To analyze the regional cerebral blood flow(rCBF) alternations in patients with anxiety disorder,comparing with normal subjects using statistical parametric mapping.Methods:99mTc ECD-brain SPECT imaging were performed in 19 anxiety disorder patients(ADP) diagnosed with CCMD 2 or ICD 10,and 23 cases with age matched normal controls for comparison.Situation of rCBF in ADP was analyzed by SPM method under the condition of increased and decreased perfusion.Results:The rCBF of bilateral temporal,superior frontal gyrus and callosal gyrus were significantly decreased in the anxiety group,and the rCBF of precentral gyrus,frontal lobe orbital part,left basal ganglia was significantly increased(P0 05).Conclusion:SPM analysis showed that significant rCBF change in anxiety disorder patients and related to disease pathophysiology.

Key concepts: Statistical parametric mapping, Cerebral blood flow, Medicine, Anxiety, Basal ganglia, Cardiology, Internal medicine, Frontal lobe

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Analysis of ECD/SPECT regional cerebral blood flow in anxiety disorder using statistical parametric mapping — Research Paper | ScholarLens