2014•Journal of Hubei University of Chinese MedicineRequires access
Clinical Observation of Xuemei'an Capsule Combined with Recombinant Human Interleukin 11 on Thrombocytopenia Causing by Peginterferonα-2a on Chronic Hepatitis C Patients
Yin Shufe
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Abstract
Objective To observe of the effect of Xuemeian combined with recombinant human interleukin-11 on pegylated interferonα-2a in treatment of chronic hepatitis C caused by thrombocytopenia curative effect observation. Methods 60 patients with chronic hepatitis C,divided into 3 groups,one with recombinant human interleukin-11,single Xuemeian group,the effect of Xuemeian combined with recombinant human interleukin-11 group. Results Recombinant human interleukin-11 efficiency is 85%,the effect of Xuemeian group effective rate is 68. 42%,the effect of Xuemeian combined with recombinant human interleukin-11 group was 90. 47%,there was significant difference between three groups( P 0. 05),in which the effect of Xuemeian combined with recombinant human interleukin-11group was significantly superior to the single use of Xuemeian group and use of recombinant human interleukin-11 group,while the single use of recombinant human interleukin-11 group is better than the effect of Xuemeian group. Conclusion Pegylated interferon α-2a in treatment of chronic hepatitis C caused by thrombocytopenia,Xuemeian combined with recombinant human interleukin-11 can improve the curative effect,reduce the adverse reaction.