Comparison of D-dimer levels between breast benign lesions and breast cancer patients

Objective To explore the changes of D-dimer levels in breast benign lesions and breast cancer females and its clinical significance.Methods 164 cases of hospitalized patients in Department of Breast Surgery were selected,of which there were 88 cases of breast benign lesions patients and 76 cases of breast cancer(35cases without lymph node metastasis,41 cases with lymph node metastasis).Plasma D-dimer level detection was performed on Sysmex CA7000 automatic blood coagulation analyzer.Results The D-dimer levels of breast cancer patients and patients with breast benign lesions were 0.28(0.18-0.45)and 0.26(0.17-0.42)mg/L respectively,and there was no significant difference(P0.05).The D-dimer levels of breast cancer patients with lymph node metastasis and without lymph node metastasis were 0.29(0.22-0.40)and 0.24(0.15-0.50)mg/L respectively,and there was no significant difference(P0.05).Conclusion D-dimer level correlates with neither breast cancer nor lymph node metastasis.