ScholarLens Back to search
2014•Journal of Chinese Practical Diagnosis and TherapyRequires access

Value of serum procalcitonin and high sensitivity C-reactive protein to the diagnosis of early neonatal sepsis

Fen Zhang

Open publisher page 0 citations

Abstract

Objective To explore the value of serum procalcitonin(PCT)and high sensitivity C-reactive protein(hsCRP)to the diagnosis of early neonatal sepsis.Methods The serum PCT and hs-CRP levels were detected by electrochemical luminescence method and immuneturbidimetric test respectively and were compared in 33cases of neonatal sepsis(sepsis group),41cases of neonatal local infection(infection group)and 38 newborns with no infection(noninfection group).Results The serum PCT levels were(12.3±11.6),(0.26±0.25)and(0.09±0.07)μg/L,and hs-CRP levels were(22.5±20.1),(3.21±3.06)and(0.85±0.33)mg/L respectively in sepsis group,infection group and noninfection group,showing significant differences among three groups(P0.05).The sensibilities of PCT and hsCRP were 84.8% and 87.9%,and the specificities of PCT and hs-CRP were 96.2% and 86.1%.Conclusions The detection of PCT and hs-CRP is helpful to the diagnosis of early neonatal sepsis.

About this research paper

What this paper is about

Objective To explore the value of serum procalcitonin(PCT)and high sensitivity C-reactive protein(hsCRP)to the diagnosis of early neonatal sepsis.Methods The serum PCT and hs-CRP levels were detected by electrochemical luminescence method and immuneturbidimetric test respectively and were compared in 33cases of neonatal sepsis(sepsis group),41cases of neonatal local infection(infection group)and 38 newborns with no infection(noninfection group).Results The serum PCT levels were(12.3±11.6),(0.26±0.25)and(0.09±0.07)μg/L,and hs-CRP levels were(22.5±20.1),(3.21±3.06)and(0.85±0.33)mg/L respectively in sepsis group,infection group and noninfection group,showing significant differences among three groups(P0.05).The sensibilities of PCT and hsCRP were 84.8% and 87.9%,and the specificities of PCT and hs-CRP were 96.2% and 86.1%.Conclusions The detection of PCT and hs-CRP is helpful to the diagnosis of early neonatal sepsis.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To explore the value of serum procalcitonin(PCT)and high sensitivity C-reactive protein(hsCRP)to the diagnosis of early neonatal sepsis.Methods The serum PCT and hs-CRP levels were detected by electrochemical luminescence method and immuneturbidimetric test respectively and were compared in 33cases of neonatal sepsis(sepsis group),41cases of neonatal local infection(infection group)and 38 newborns with no infection(noninfection group).Results The serum PCT levels were(12.3±11.6),(0.26±0.25)and(0.09±0.07)μg/L,and hs-CRP levels were(22.5±20.1),(3.21±3.06)and(0.85±0.33)mg/L respectively in sepsis group,infection group and noninfection group,showing significant differences among three groups(P0.05).The sensibilities of PCT and hsCRP were 84.8% and 87.9%,and the specificities of PCT and hs-CRP were 96.2% and 86.1%.Conclusions The detection of PCT and hs-CRP is helpful to the diagnosis of early neonatal sepsis.

Key concepts: Procalcitonin, Medicine, Sepsis, Neonatal sepsis, C-reactive protein, Gastroenterology, Internal medicine, Neonatal infection

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Value of serum procalcitonin and high sensitivity C-reactive protein to the diagnosis of early neonatal sepsis — Research Paper | ScholarLens