Correlation between homocysteine level and hs-CRP level in patients with acute coronary syndrome
Ding Xiao
Abstract
Ding Xiao
Abstract
Objective:To evaluate the plasma homocysteine and hs-CRP levels and their relation in patients with acute coronary syndrome(ACS).Methods: The Hcy and hs-CRP levels were measured in 60 ACS patients and 30 normal.Results:The levels of plasma Hcy and hsCRP were significantly increased in ACS patients compared with control group(P0.05).The plasma hs-CRP and Hcy levels increased in AMI group compared with those of UAP group(P0.05).The correlation between homocysteine level and hs-CRP level in ACS patients was positive(r=0.444,P0.01).While there was no correlation between hs-CRP level and Hcy levels in control group(P0.05).Conclusion:Homocysteine may play an important role in the occurrence of ACS by mediating hs-CRP expression as an inflammatory medium.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Objective:To evaluate the plasma homocysteine and hs-CRP levels and their relation in patients with acute coronary syndrome(ACS).Methods: The Hcy and hs-CRP levels were measured in 60 ACS patients and 30 normal.Results:The levels of plasma Hcy and hsCRP were significantly increased in ACS patients compared with control group(P0.05).The plasma hs-CRP and Hcy levels increased in AMI group compared with those of UAP group(P0.05).The correlation between homocysteine level and hs-CRP level in ACS patients was positive(r=0.444,P0.01).While there was no correlation between hs-CRP level and Hcy levels in control group(P0.05).Conclusion:Homocysteine may play an important role in the occurrence of ACS by mediating hs-CRP expression as an inflammatory medium.
Key concepts: Medicine, Homocysteine, Acute coronary syndrome, Internal medicine, Plasma levels, Plasma homocysteine, C-reactive protein, Correlation