2007Xinxueguan kangfu yixue zazhiRequires access

Correlation between homocysteine level and hs-CRP level in patients with acute coronary syndrome

Ding Xiao

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Abstract

Objective:To evaluate the plasma homocysteine and hs-CRP levels and their relation in patients with acute coronary syndrome(ACS).Methods: The Hcy and hs-CRP levels were measured in 60 ACS patients and 30 normal.Results:The levels of plasma Hcy and hsCRP were significantly increased in ACS patients compared with control group(P0.05).The plasma hs-CRP and Hcy levels increased in AMI group compared with those of UAP group(P0.05).The correlation between homocysteine level and hs-CRP level in ACS patients was positive(r=0.444,P0.01).While there was no correlation between hs-CRP level and Hcy levels in control group(P0.05).Conclusion:Homocysteine may play an important role in the occurrence of ACS by mediating hs-CRP expression as an inflammatory medium.

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Objective:To evaluate the plasma homocysteine and hs-CRP levels and their relation in patients with acute coronary syndrome(ACS).Methods: The Hcy and hs-CRP levels were measured in 60 ACS patients and 30 normal.Results:The levels of plasma Hcy and hsCRP were significantly increased in ACS patients compared with control group(P0.05).The plasma hs-CRP and Hcy levels increased in AMI group compared with those of UAP group(P0.05).The correlation between homocysteine level and hs-CRP level in ACS patients was positive(r=0.444,P0.01).While there was no correlation between hs-CRP level and Hcy levels in control group(P0.05).Conclusion:Homocysteine may play an important role in the occurrence of ACS by mediating hs-CRP expression as an inflammatory medium.

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Available abstract

Objective:To evaluate the plasma homocysteine and hs-CRP levels and their relation in patients with acute coronary syndrome(ACS).Methods: The Hcy and hs-CRP levels were measured in 60 ACS patients and 30 normal.Results:The levels of plasma Hcy and hsCRP were significantly increased in ACS patients compared with control group(P0.05).The plasma hs-CRP and Hcy levels increased in AMI group compared with those of UAP group(P0.05).The correlation between homocysteine level and hs-CRP level in ACS patients was positive(r=0.444,P0.01).While there was no correlation between hs-CRP level and Hcy levels in control group(P0.05).Conclusion:Homocysteine may play an important role in the occurrence of ACS by mediating hs-CRP expression as an inflammatory medium.

Key concepts: Medicine, Homocysteine, Acute coronary syndrome, Internal medicine, Plasma levels, Plasma homocysteine, C-reactive protein, Correlation

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