Analysis on high risk factors of bronchopulmonary dysplasia in very low birth weight infants

Objective:To explore the clinical high risk factors of bronchopulmonary dysplasia(BPD) in very low birth weight infants.Methods:The clinical data of 199 very low birth weight infants who were treated in NICU of the hospital were analyzed retrospectively,then they were divided into BPD group and non-BPD group;the probable risk factors of BPD were analyzed.Results:Among 199 very low birth weight infants,48 infants were diagnosed as BPD,the morbidity was 24.1%.There were statistically significant differences in the time of mechanical ventilation,the time of oxygen inhalation,the time of oxygen inhalation with oxygen concentration40%,intrauterine infection,combined with patent ductus arteriosus,and nosocomial infection between BPD group and non-BPD group(P0.05);the results of logistic regression analysis showed that the time of mechanical ventilation,intrauterine infection,and the time of oxygen inhalation with oxygen concentration40% were the risk factors of BPD.Conclusion:Preventing intrauterine infection can reduce the morbidity of BPD,mechanical ventilation for a long time and oxygen inhalation with high oxygen concentration are high risk factors of BPD.