The Risk Factors for Bronchopulmonary Dysplasia in Very Low Birth Weight Infants(VLBWI)

Objective:To study the incidence,risk factors,prophylaxis and treatment for bronchopulmonary dysplasia(BPD)in very low birth weight infants.Methods:From January 2006 to September 2009,75 very low birth weight infants in NICU were enrolled in the study.13 with BPD were compared to 62 ones without BPD in the clinical materials.Results:The total incidence of BPD in the very low birth weight infants was 17.33%,and 33.33% in those infants with mechanical ventilation,10.34% in those infants with nasal continuous positive airway pressure(nCPAP)combined with pulmonary surfactant(PS).The gestational age and birth weight of BPD group were lower than those without BPD,and the rates of amniocentesis and complicated PDA in BPD group were higher than those of the control(P0.05).The use of PS,reducing fluid intake during the first ten days of life,controlling pulmonary infection,managing anemia have been found different between the two groups(P0.05).Conclusion:Preventing premature labor,nCPAP combining with PS,reducing fluid intake during the first ten days of life,managing anemia effective in preventing BPD.