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2002•Dalian Yike Daxue xuebaoRequires access

Analysis of the effect of transforming growth factor-β on the pathogenesis of rheumatoid arthritis

Gao Ze-bin

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Abstract

Objective: To analysis the main effect of transforming growth factor-β(TGF-β) on rheumatoid arthritis (RA) . Methods : To detect serum concentrations of TGF-β of 80 patients with RA hospitalizing from Feb. to Jun. 2001 and 20 normal persons using ABC-ELISA. Results : The blood levels of TGF-β of the patients were lower than those of normal persons significantly ( P 0.01). Conclusions: TGF-β may be a protective factor in the pathogenesis of RA .

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What this paper is about

Objective: To analysis the main effect of transforming growth factor-β(TGF-β) on rheumatoid arthritis (RA) . Methods : To detect serum concentrations of TGF-β of 80 patients with RA hospitalizing from Feb. to Jun. 2001 and 20 normal persons using ABC-ELISA. Results : The blood levels of TGF-β of the patients were lower than those of normal persons significantly ( P 0.01). Conclusions: TGF-β may be a protective factor in the pathogenesis of RA .

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Available abstract

Objective: To analysis the main effect of transforming growth factor-β(TGF-β) on rheumatoid arthritis (RA) . Methods : To detect serum concentrations of TGF-β of 80 patients with RA hospitalizing from Feb. to Jun. 2001 and 20 normal persons using ABC-ELISA. Results : The blood levels of TGF-β of the patients were lower than those of normal persons significantly ( P 0.01). Conclusions: TGF-β may be a protective factor in the pathogenesis of RA .

Key concepts: Pathogenesis, Rheumatoid arthritis, Transforming growth factor, Medicine, Internal medicine, Rheumatoid factor, Immunology, Arthritis

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