2012Journal of Clinical Medicine in PracticeRequires access

A clinical study of sodium ozagrel injection combined with low molecular weight heparin sodium on progressive cerebral infarction

LU Lanxiang

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Abstract

Objective To observe the therapeutic effect of sodium ozagrel injection combined with low molecular weight heparin sodium in the treatment of progressive cerebral infarction.Methods Eighty patients were randomly divided into treatment group and control group,which were administered sodium ozagrel+ low molecular weight heparin sodium and low molecular weight heparin sodium,respectively.The degree of neurological deficit were assessed according to the U.S.National Institutes of Health Stroke Scale(NIHSS) score and activities of daily living(ADL) in two groups before treatment,and 14 days after treatment.Results The excellence rates in the treatment and control group were 69.77% and 47.62%,respectively 14 days after treatment. The rate of improvement in the combined group was better than that of the control group(P0.05).No complications of gastrointestinal bleeding,intracranial hemorrhage were identifed in both groups.Conclusion Sodium ozagrel injection combined with low molecular weight heparin sodium is safe and reliable in treating progressive cerebral infarction,which is worthy of clinical use.

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Objective To observe the therapeutic effect of sodium ozagrel injection combined with low molecular weight heparin sodium in the treatment of progressive cerebral infarction.Methods Eighty patients were randomly divided into treatment group and control group,which were administered sodium ozagrel+ low molecular weight heparin sodium and low molecular weight heparin sodium,respectively.The degree of neurological deficit were assessed according to the U.S.National Institutes of Health Stroke Scale(NIHSS) score and activities of daily living(ADL) in two groups before treatment,and 14 days after treatment.Results The excellence rates in the treatment and control group were 69.77% and 47.62%,respectively 14 days after treatment. The rate of improvement in the combined group was better than that of the control group(P0.05).No complications of gastrointestinal bleeding,intracranial hemorrhage were identifed in both groups.Conclusion Sodium ozagrel injection combined with low molecular weight heparin sodium is safe and reliable in treating progressive cerebral infarction,which is worthy of clinical use.

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Available abstract

Objective To observe the therapeutic effect of sodium ozagrel injection combined with low molecular weight heparin sodium in the treatment of progressive cerebral infarction.Methods Eighty patients were randomly divided into treatment group and control group,which were administered sodium ozagrel+ low molecular weight heparin sodium and low molecular weight heparin sodium,respectively.The degree of neurological deficit were assessed according to the U.S.National Institutes of Health Stroke Scale(NIHSS) score and activities of daily living(ADL) in two groups before treatment,and 14 days after treatment.Results The excellence rates in the treatment and control group were 69.77% and 47.62%,respectively 14 days after treatment. The rate of improvement in the combined group was better than that of the control group(P0.05).No complications of gastrointestinal bleeding,intracranial hemorrhage were identifed in both groups.Conclusion Sodium ozagrel injection combined with low molecular weight heparin sodium is safe and reliable in treating progressive cerebral infarction,which is worthy of clinical use.

Key concepts: Medicine, Low molecular weight heparin, Cerebral infarction, Sodium, Heparin, Anesthesia, Heparin sodium, Therapeutic effect

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