Observation of Protecting the Renal Function in Patients with Diabetic Nephropathy by Reducing Serum Lipids
Jun Huang
Abstract
Jun Huang
Abstract
Objective To investigate the effect of atorvastatin in protecting the renal function in patients with diabetic nephropathy by reducing serum lipids.Methods 160 patients of diabetic nephropathy with hyperlipemia were divided into treatment group(n=82) and control group(n=78) randomly.Atorvastatin was taken in the treatment group.The drug treatment programs of chronic renal failure were the same in the two groups.At the observation period of 12 months,serum lipids and renal function were compared between the two groups.Results Serum lipids(P 0.001) and the fall of eGFR(P 0.01) in the treatment group were lower than those in the control group significantly.Conclusion Reducing serum lipids in patients with diabetic nephropathy can delay the progress of renal failure.Serum lipids shall be controlled to standard level as soon as possible.
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Objective To investigate the effect of atorvastatin in protecting the renal function in patients with diabetic nephropathy by reducing serum lipids.Methods 160 patients of diabetic nephropathy with hyperlipemia were divided into treatment group(n=82) and control group(n=78) randomly.Atorvastatin was taken in the treatment group.The drug treatment programs of chronic renal failure were the same in the two groups.At the observation period of 12 months,serum lipids and renal function were compared between the two groups.Results Serum lipids(P 0.001) and the fall of eGFR(P 0.01) in the treatment group were lower than those in the control group significantly.Conclusion Reducing serum lipids in patients with diabetic nephropathy can delay the progress of renal failure.Serum lipids shall be controlled to standard level as soon as possible.
Key concepts: Medicine, Diabetic nephropathy, Atorvastatin, Blood lipids, Renal function, Nephropathy, Internal medicine, Diabetes mellitus