Study on Correlation of the Transrectal Ultrasound Prostate Biopsy of 13-core and the Serum Concentration of PSA in Diagnosis of Prostate Cancer

Objective To assess the correlation of transrectal ultrasound prostate biopsy of 13-core and the serum concentration of prostate specific antigen (PSA) in diagnosis of prostate cancer. Methods 105 patients treated with the transrectal ultrasound prostate biopsy of 13-core were retrospectively analyzed, and their detection rates of prostate cancer were assessed. The correlation between the concentration of PSA and prostate cancer were analyzed. Results The positive rate of prostate cancer with PSA level at 4.0 ng/mL was 12.6%, 4.0 ≤ PSA 10 ng/mL was 23.8%, 10 ≤ PSA 20 ng/mL was 12.6%, and ≥20 ng/mL was 12.6%, respectively. The positive rate among those four groups were significantly different (P 0.05). Conclusions The serum concentration of PSA and biopsy-positive results for prostate cancer are significantly associated. The serum concentration of PSA is a useful marker to guide the implementation of transrectal ultrasound prostate biopsy in the diagnosis of prostate cancer.