The clinical observation of tracheal extubation response of remifentanil infusion in nasal endoscopic surgery

Objective To observe the effect of tracheal extubation response of remifentanil infusion in nasal endoscopic operation. Methods Sixty six patients were divided into three groups: The infusion rate of remifentanil was respectively 0. 075 μg·( kg·min)-1( group R1),0. 05 μg·( kg·min)-1( group R2) and control group( group C) until 5mins after tracheal extubation in the recovery period when operation finished. Hemodynamics,tolerance of tracheal tube and buking,the BP and HR,recovery time were evaluated when before operation( T0),before tracheal extubation( T1),1 min after tracheal extubation( T2),3 mins after tracheal extubation( T3),5 mins after tracheal extubation( T4). Results The incidence rate of buking and muscle inflexible was significant lower in group R1 and group R2 than that group C. The patients who could be tolerant tracheal tube in in group R1 and group R2. The recovery time of C group was shorter than remifentanil groups. Conclusion Continous remifentanil infusion at 0. 05-0. 75 μg·( kg·min)-1can effectively prevent hemodynamics reaction to tracheal extubation in patients undergoing TIVA anesthesia in nasal endoscopic operation.