2011Zhongguo yiyuan ganranxue zazhiRequires access

Value of RPR and TPPA testing for syphilis diagnosis and curative effect

WU Jing-song

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Abstract

OBJECTIVE To evaluate the RPR(Rapid plasma reagin circle test) and TPPA(treponema pallidum Antibody particles agglutinate experiment) detection antibody particles of syphilis diagnosis and curative effect of value.METHODS A total of 300 cases of syphilis,100 cases of non-syphilis patients and 50 case of normal with RPR on TPPA joint test and analysis were performed.RESULTS Among the 172 cases of syphilis of phaseⅠ with RPR and TPPA,the positive rates were 83.1% and 100%,respectively,in the 117 cases of syphilis on the phaseⅡwith RPR and TPPA,the positive rates were 100.0% and 100.0%,respectively,11 cases of syphilis of preclinical with RPR and TPPA,the positive rates were 84.6% and 100.0%,respectively,100 cases of non-syphilis patients with the positive rates of the RPR and TPPA respectively 3.0% and 0,50 cases of normal with RPR and TPPA positive for 0 all.CONCLUSION The RPR and TPPA syphilis diagnosis is fast and effective method on diagnosis of syphilis,TPPA,as confirmed diagnose test in the specificity and sensitivity is significantly higher than RPR,but RPR is significantly better than TPPA in clinical therapeutic effect observation.

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OBJECTIVE To evaluate the RPR(Rapid plasma reagin circle test) and TPPA(treponema pallidum Antibody particles agglutinate experiment) detection antibody particles of syphilis diagnosis and curative effect of value.METHODS A total of 300 cases of syphilis,100 cases of non-syphilis patients and 50 case of normal with RPR on TPPA joint test and analysis were performed.RESULTS Among the 172 cases of syphilis of phaseⅠ with RPR and TPPA,the positive rates were 83.1% and 100%,respectively,in the 117 cases of syphilis on the phaseⅡwith RPR and TPPA,the positive rates were 100.0% and 100.0%,respectively,11 cases of syphilis of preclinical with RPR and TPPA,the positive rates were 84.6% and 100.0%,respectively,100 cases of non-syphilis patients with the positive rates of the RPR and TPPA respectively 3.0% and 0,50 cases of normal with RPR and TPPA positive for 0 all.CONCLUSION The RPR and TPPA syphilis diagnosis is fast and effective method on diagnosis of syphilis,TPPA,as confirmed diagnose test in the specificity and sensitivity is significantly higher than RPR,but RPR is significantly better than TPPA in clinical therapeutic effect observation.

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Available abstract

OBJECTIVE To evaluate the RPR(Rapid plasma reagin circle test) and TPPA(treponema pallidum Antibody particles agglutinate experiment) detection antibody particles of syphilis diagnosis and curative effect of value.METHODS A total of 300 cases of syphilis,100 cases of non-syphilis patients and 50 case of normal with RPR on TPPA joint test and analysis were performed.RESULTS Among the 172 cases of syphilis of phaseⅠ with RPR and TPPA,the positive rates were 83.1% and 100%,respectively,in the 117 cases of syphilis on the phaseⅡwith RPR and TPPA,the positive rates were 100.0% and 100.0%,respectively,11 cases of syphilis of preclinical with RPR and TPPA,the positive rates were 84.6% and 100.0%,respectively,100 cases of non-syphilis patients with the positive rates of the RPR and TPPA respectively 3.0% and 0,50 cases of normal with RPR and TPPA positive for 0 all.CONCLUSION The RPR and TPPA syphilis diagnosis is fast and effective method on diagnosis of syphilis,TPPA,as confirmed diagnose test in the specificity and sensitivity is significantly higher than RPR,but RPR is significantly better than TPPA in clinical therapeutic effect observation.

Key concepts: Syphilis, Rapid plasma reagin, Medicine, Treponema, Internal medicine, Immunology, Human immunodeficiency virus (HIV)

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