2008•Medical Journal of Chinese People's HealthRequires access

An experiment study of Duzhongyechun in prevention of osteoporosis on ovariectomized famale rats

Suo Xin-hua

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Abstract

Objective:To study the effect of Duzhongyechun on the bone mineral density of rats without ovaria and the level of estrogen,IL-6 in serums through the osteoporosis models of the rats.Methods:Reproduce the osteoporosis model of ovariectomized Wistar rats and receive Duzhongyechun therapy.After 12 week therapy bone mineral density,serum estrogen and IL-6 were measured.Results: The bone mineral density of ovariectomized rats decreased significantly.Compared with the model group,the bone mineral density and the content of serum estrogen(E2) increased significantly(P0.05),the content of serum IL-6 decreased remarkably(P0.05)after 12 week therapy using Duzhongyechun.Conclusions: Duzhongyechun can notably increase the bone mineral density and the content of serum estrogen of rats without ovaria,control the levels of IL-6 in serum.

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Objective:To study the effect of Duzhongyechun on the bone mineral density of rats without ovaria and the level of estrogen,IL-6 in serums through the osteoporosis models of the rats.Methods:Reproduce the osteoporosis model of ovariectomized Wistar rats and receive Duzhongyechun therapy.After 12 week therapy bone mineral density,serum estrogen and IL-6 were measured.Results: The bone mineral density of ovariectomized rats decreased significantly.Compared with the model group,the bone mineral density and the content of serum estrogen(E2) increased significantly(P0.05),the content of serum IL-6 decreased remarkably(P0.05)after 12 week therapy using Duzhongyechun.Conclusions: Duzhongyechun can notably increase the bone mineral density and the content of serum estrogen of rats without ovaria,control the levels of IL-6 in serum.

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Available abstract

Objective:To study the effect of Duzhongyechun on the bone mineral density of rats without ovaria and the level of estrogen,IL-6 in serums through the osteoporosis models of the rats.Methods:Reproduce the osteoporosis model of ovariectomized Wistar rats and receive Duzhongyechun therapy.After 12 week therapy bone mineral density,serum estrogen and IL-6 were measured.Results: The bone mineral density of ovariectomized rats decreased significantly.Compared with the model group,the bone mineral density and the content of serum estrogen(E2) increased significantly(P0.05),the content of serum IL-6 decreased remarkably(P0.05)after 12 week therapy using Duzhongyechun.Conclusions: Duzhongyechun can notably increase the bone mineral density and the content of serum estrogen of rats without ovaria,control the levels of IL-6 in serum.

Key concepts: Ovariectomized rat, Bone mineral, Osteoporosis, Internal medicine, Estrogen, Endocrinology, Bone density, Bone mineral content

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