2004•Journal of China Medical ImagingRequires access

Clinicopathologic and the imaging manifestations of central neurocytoma

Bo Luo

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Abstract

Objective To explore the clinicopathologic and the imaging features of central neurocytomaCNC in order to improve the diagnosis. Materials and Methods Six cases of CNC were analyzed retrospectively also correlate with pathological features. Results There were 4 males and 2 females and the age ranged from 30 to 63 years oldthe mean age was 45 years old. The tumors were primarily located in the lateral ventricles close to the foramina of Monra and attached to the lateral wall of the lateral ventricle or septum pellucidum with a broad base. CT scan displayed isointense or slightly hyperintense mass with multiple small cystic features and patch like calcifications. The tumors revealed isointense or slightly hypointense signal on T1WI and heterogeneous hyperintense signal on T2WI with slight to moderate enhancement. Results of immunohistochemical study were positive for synptophysinSyn glial fibrillary acid proteinGFAP and neuron specific enclaseNSE. Conclusion The tumors were mainly located in the anterior region of ventricles or close to the foramina of Monra and their imaging features were characteristic. CNC should be taken into consideration if tumor arises from the specific region.

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Objective To explore the clinicopathologic and the imaging features of central neurocytomaCNC in order to improve the diagnosis. Materials and Methods Six cases of CNC were analyzed retrospectively also correlate with pathological features. Results There were 4 males and 2 females and the age ranged from 30 to 63 years oldthe mean age was 45 years old. The tumors were primarily located in the lateral ventricles close to the foramina of Monra and attached to the lateral wall of the lateral ventricle or septum pellucidum with a broad base. CT scan displayed isointense or slightly hyperintense mass with multiple small cystic features and patch like calcifications. The tumors revealed isointense or slightly hypointense signal on T1WI and heterogeneous hyperintense signal on T2WI with slight to moderate enhancement. Results of immunohistochemical study were positive for synptophysinSyn glial fibrillary acid proteinGFAP and neuron specific enclaseNSE. Conclusion The tumors were mainly located in the anterior region of ventricles or close to the foramina of Monra and their imaging features were characteristic. CNC should be taken into consideration if tumor arises from the specific region.

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Available abstract

Objective To explore the clinicopathologic and the imaging features of central neurocytomaCNC in order to improve the diagnosis. Materials and Methods Six cases of CNC were analyzed retrospectively also correlate with pathological features. Results There were 4 males and 2 females and the age ranged from 30 to 63 years oldthe mean age was 45 years old. The tumors were primarily located in the lateral ventricles close to the foramina of Monra and attached to the lateral wall of the lateral ventricle or septum pellucidum with a broad base. CT scan displayed isointense or slightly hyperintense mass with multiple small cystic features and patch like calcifications. The tumors revealed isointense or slightly hypointense signal on T1WI and heterogeneous hyperintense signal on T2WI with slight to moderate enhancement. Results of immunohistochemical study were positive for synptophysinSyn glial fibrillary acid proteinGFAP and neuron specific enclaseNSE. Conclusion The tumors were mainly located in the anterior region of ventricles or close to the foramina of Monra and their imaging features were characteristic. CNC should be taken into consideration if tumor arises from the specific region.

Key concepts: Central neurocytoma, Medicine, Septum pellucidum, Lateral ventricles, Pathological, Pathology, Glial fibrillary acidic protein, Anatomy

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