Total IgE and Specific IgE in Sera with Allergic Diseases

Objective To provide the immunological basis of prevention from allergic diseases. Methods The total IgE and specific IgE in sera of 146 cases with allergic diseases were detected by ELISA, among them 86 cases were aeroallergenrelated and 60 cases food-allergenrelated. Results Positive results were obtained in 102 cases among the 146 cases, the positive rate was 69.8%. It was proved that 84.8%(73/86) was aeroallergen-positive, 47.5%( 29/61 ) was food-allergen-positive, and 26.8%(11/41) was both aero and food-allergen-positive.The positive rate of dermatophagoides pteronyssinus and dermatophagoides farinae was higher than the other aeroallergens,while the positive rate of fish was the highest among the food allergens. We didn't observe obvious seasonal diffence among the positive rates of the three pollen allergens. Conclusions It is of clinical significance to test the serum total IgE and specific IgE in management of allergy. No correlation between the positive rates of pollen allergens and pollen seasons is found in the present study.