Transcatheter arterial chemoembolization combined three-dimensional conformal radiotherapy in treatment of primary liver cancer

Objective To explore the clinical efficacy of hepatic arterial embolization(TACE)combined with threedimensional conformal radiotherapy(3DCRT)for hepatocellular carcinoma(HCC).Methods According to the order of admission,120patients of unresectable hepatocellular carcinoma were randomly divided into observation group and control group(n=60).Control group received TACE treatment alone,and the observation group in the TACE treatment based uplink 3DCRT treatment.On two recent overall response rate(complete response+partial remission,namely:CR+PR),and 1year after treatment,two-year,3-year survival and other efficacy measures were compared.Results The total effective rate of observation group and control group were 89.23%and 46.51%.There was a statistically significant difference between the groups(P0.05).2-year survival rate of observation group and control group were 58.3% and33.3%(χ2=8.471,P=0.005).The 1-year and 3-year survival rate in the observation group were 65.0% and 15.0%and that of the control group was 68.3%and 18.3%(1-yearχ2=1.83,P=0.233;3-yearχ2=0.25,P=0.803).Conclusion TACE combined with 3DCRT was with good effect for hepatocellular carcinoma,.