Experimental study on germicidal efficacy and toxicity of pen-xiao-jing

Objective In order to Rnow its physocochemical properties germicidal officaey and toxicity.Methods Carrier qantitative method and animal tast method were used to study its germicidal officacy and toxicity.Results The results showed that the killing rates of Eschenichia coli and Staphyloclccus aureus on clath strips espoxed to Pen-Xiao-Jing solution conlaining available iodine 100mg/L for 5 min and candida albicans on cloth strips exposed to the disinfectant solution containing available iodine 600mg/L for 20min were99.90%.The available iodine content of its solution decreased by 5.76% after stoning at 54℃ for 14 days.The mouse oral LD50 of the disinfectant was5000ms/Kg.So it belongs to non-toxic class.Its accumulation coefficient K was5,So it belongs to weak cumulative toxicity.It was ont irritative to rabbit skin.Both mouse bone marrow micronucleus test and sperm aberration test were negative.Conclusion The compound disinfectant has good germicidal efficacy and toxicity and is stable.