Clinical observation of Propess for cervical ripening and induction of labor at full-term pregnancy

【Objective】To observe the effects of prostaglandin E2(Propess) for cervical ripening and induction of labor at full-term pregnancy.【Methods】 100 primiparae were divided into two groups randomly.The experimental group was placed a piece of Propess in posterior fornix,the control group was treated with 0.5% intravenous oxytocin in the induction process.The change of cervical ripening(Bishop),labor induction rate,the average interval from medication to in labor,the total stages of labor,postpartum hemorrhage,cesarean section rate,neonatal asphyxia rate were observed as the clinical evaluation after the treatment.【Results】 12 hours after administration,Bishop and labor induction rate in experimental group were higher than in control group;the average interval from medication to in labor and the delivery time were shorter;the rate of vaginal delivery increased,the cesarean section rate decreased;Postpartum hemorrhage and neonatal asphyxia had no significant differences between two groups.【Conclusions】Prostaglandin E2(Propess) is a kind of effective drug for cervix maturing and labor induction which is worthy of clinical application.