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Determination of cystatin C in serum and its clinical significance

Qiao Lin

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Abstract

Objective To investigate the clinical significance of serum cystatin C as a marker of glomerular filtration function.Methods Serum cystatin C was measured by ELISA. On the same time, serum creatinine and endogenous creatinine clearance were measured in all patients.Then the correlation and diagnostic sensibility of them were analyzed.Results Serum cystatin C and Ccr were significantly correlated.The diagnostic sensibility of serum cystatin C is better than of Scr.Conclusion Serum cystatin C is a reliable and susceptible marker of glomerular filtration function.

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Objective To investigate the clinical significance of serum cystatin C as a marker of glomerular filtration function.Methods Serum cystatin C was measured by ELISA. On the same time, serum creatinine and endogenous creatinine clearance were measured in all patients.Then the correlation and diagnostic sensibility of them were analyzed.Results Serum cystatin C and Ccr were significantly correlated.The diagnostic sensibility of serum cystatin C is better than of Scr.Conclusion Serum cystatin C is a reliable and susceptible marker of glomerular filtration function.

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Available abstract

Objective To investigate the clinical significance of serum cystatin C as a marker of glomerular filtration function.Methods Serum cystatin C was measured by ELISA. On the same time, serum creatinine and endogenous creatinine clearance were measured in all patients.Then the correlation and diagnostic sensibility of them were analyzed.Results Serum cystatin C and Ccr were significantly correlated.The diagnostic sensibility of serum cystatin C is better than of Scr.Conclusion Serum cystatin C is a reliable and susceptible marker of glomerular filtration function.

Key concepts: Cystatin C, Renal function, Creatinine, Cystatin, Clinical significance, Internal medicine, Medicine, Endocrinology

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