Prospective randomized controlled study on complex treatment of traditional chinese medicine to advanced primary hepatocarcinoma

Objective:To observe the effects of complex treatment with traditional chinese medicine on advanced primary hepatocarcinoma.Methods:97 patient with advanced primary hepatocarcinoma were randomly and parallelly divided into experimental group and control group.Patients in experimental group were treated by complex treatment with traditional chinese medicine,and patients in control group were treated by western medicine.Then the curative effect of near term and long term,the side effect and toxicity,the onset time and duration of analgesia as well as the quantity of life(QOL)were determined.Results:No significant difference of disease control rate was shown between the two groups.The rate of side effect and toxicity in experimental group was lower than that in control group(P0.05).The mean duration of analgesia of experimental group was(10.37±2.18)h,which was higher than that in control group(P0.05),but no considerable difference of the onset time of analgesia was shown between the two groups.Karnofsky scores of experimental group was higher than that in control group after treatment(P0.05).After the treatment,the patients in experimental group showed an enhanced body function,alleviated symptom and improved total QOL compared with patients in control group(P0.05).No marked difference of 3-month survival rate was shown between the two groups(P0.05).The 0.5-and 1-year survival rate in exper imental group were 65.9%and 38.6%respectively,superior to those in control group(42.5%and 18.1%repectively)(P0.05).The median survival times in the experimental and control group were 8.9 and 5.3 months respectively(P0.05).Conclusion:Complex treatment of traditional chinese medicine has lower side effect and toxicity and can prolong the duration of anslgesia,improve the QOL and raise the long-term survival rate.It is an effective method of treating the patients with advanced primary hepatocarcinoma.