Effect of primary percutaneous coronary interventions on left ventricular Remodeling in patients with acute myocardial infarction accompanied with right bundle branch block

Objective To evaluate the effect of primary percutaneous coronary interventions on left ventricular remodeling in patients with acute myocardial infarction(AMI) accompanied with the newly appeared persistent right bundle branch block(RBBB). Methods 45 patients with acute myocardial infarction and newly appeared persistent RBBB admitted in our hospital were studied as primary PCI group. 41 patients with AMI with bundle branch block admitted in the same period served as thrombolytic therapy group. The indices of left ventricular remodeling including left ventricular end diastolic volume index, Left ventricular end systolic volume index, and left ventricular ejection fraction were measured by ultrasonic cardiogram on 24 h,1week,1 month and 3 months after onset of AMI. Results At 1 month and 3 months after primary PCI, the parameters of cardiac performance were decreased significantly and left ventricular ejection fraction improved in primary PCI compared with those in thrombolytic therapy group. Left ventricular end diastolic volume index(63.4±5.8)ml/m2 vs(67.3±6.4)ml/m2,left ventricular end systolic volume index(30.5±3.4)ml/m2 vs(34.6±4.0)ml/m2 and left ventricular ejection fraction(0.53±0.04)% vs (0.50±0.02)% that were notable in primary PCI group at 3 months after PCI. Conclusion Primary percutaneous coronary interventions could attenuate left ventricular remodeling and improve left ventricular function.