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The Effects of Direct Percutaneous Coronary Intervention on Left Ventricular Remodeling after Acute Myocardial Infarction

Yong Lu

Abstract

Objective:To investigate the effects of direct percutaneous coronary intervention(PCI)and routine medical therapy on left ventricular remodeling after acute myocardial infarction(AMI).Mothods:A total of 65 patients were investigated by echocardiography at the first-month and 1-2 year after AMI.Results:There were significant decreased in grade of NYHA and re-hospitalization and mortality rate(P0.05)in patients received direct PCI compared with patients received routine medical therapy.Left ventricular end-systolic volume(LVESV)and wall motion index(WMI)significantly decreased(P0.01),and left ventricular ejection fraction(LVEF)and spherical index(SI)increased(P0.01).There was significant difference in LVESV and LVEF and SI in patients received routine medical therapy(P0.01),however,not so in patients received direct PCI(P0.05)between the first month and 1-2 year after AMI.Conclusions:Direct PCI can attenuate left ventricular remodeling after AMI.

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Key concepts: Medicine, Conventional PCI, Cardiology, Percutaneous coronary intervention, Myocardial infarction, Internal medicine, Ejection fraction, Ventricular remodeling