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Analysis on the Conduction Velocity Distribution of Motor Nerve and Characteristic of TCM Syndromes of 148 Patients with Diabetes II

Nan Jiang

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Abstract

Objective To discuss the evaluation value of conduction velocity distribution (CVD) test with computer-assisted collision technique in diabetic peripheral neuropathy patients and its relationship with TCM syndromes. Methods Totally 148 patients with diabetes Ⅱ were selected to receive CVD test and were compared with NCV test. Furthermore they were classified into TCM syndromes, given score in 5 grades and given the related lab tests. Results The rate of CVD abnormality was 86.1%, which was remarkably higher than MCV or SCV test synchronously (P0.01). The course and 2hPBG were the independent risk factors for CVD abnormality. There was a negative correlation between blood sugar and motor nerve conduction velocities. The frequency of Yin-deficiency syndrome and blood-stasis syndrome was more than 50%. The proportion of Yang-deficiency arose in the longer-course group (P0.05). Besides, the proportion of Yang-deficiency syndrome and blood-stasis syndrome were significantly higher in the group aged60 than in the group aged≤60(P0.01). The risk of CVD abnormality increased as the scores of Yang-deficiency, blood-stasis and phlegm-damp upgraded. Conclusion CVD test with computer-assisted collision technique is more sensitive than NCV test and can serve as an early and effective index for evaluation of DPN. The course and blood glucose are the independent risk factors for CVD abnormality. Yang-deficiency, blood-stasis and phlegm-damp syndromes have certain effects on the parameters of CVD.

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Objective To discuss the evaluation value of conduction velocity distribution (CVD) test with computer-assisted collision technique in diabetic peripheral neuropathy patients and its relationship with TCM syndromes. Methods Totally 148 patients with diabetes Ⅱ were selected to receive CVD test and were compared with NCV test. Furthermore they were classified into TCM syndromes, given score in 5 grades and given the related lab tests. Results The rate of CVD abnormality was 86.1%, which was remarkably higher than MCV or SCV test synchronously (P0.01). The course and 2hPBG were the independent risk factors for CVD abnormality. There was a negative correlation between blood sugar and motor nerve conduction velocities. The frequency of Yin-deficiency syndrome and blood-stasis syndrome was more than 50%. The proportion of Yang-deficiency arose in the longer-course group (P0.05). Besides, the proportion of Yang-deficiency syndrome and blood-stasis syndrome were significantly higher in the group aged60 than in the group aged≤60(P0.01). The risk of CVD abnormality increased as the scores of Yang-deficiency, blood-stasis and phlegm-damp upgraded. Conclusion CVD test with computer-assisted collision technique is more sensitive than NCV test and can serve as an early and effective index for evaluation of DPN. The course and blood glucose are the independent risk factors for CVD abnormality. Yang-deficiency, blood-stasis and phlegm-damp syndromes have certain effects on the parameters of CVD.

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Available abstract

Objective To discuss the evaluation value of conduction velocity distribution (CVD) test with computer-assisted collision technique in diabetic peripheral neuropathy patients and its relationship with TCM syndromes. Methods Totally 148 patients with diabetes Ⅱ were selected to receive CVD test and were compared with NCV test. Furthermore they were classified into TCM syndromes, given score in 5 grades and given the related lab tests. Results The rate of CVD abnormality was 86.1%, which was remarkably higher than MCV or SCV test synchronously (P0.01). The course and 2hPBG were the independent risk factors for CVD abnormality. There was a negative correlation between blood sugar and motor nerve conduction velocities. The frequency of Yin-deficiency syndrome and blood-stasis syndrome was more than 50%. The proportion of Yang-deficiency arose in the longer-course group (P0.05). Besides, the proportion of Yang-deficiency syndrome and blood-stasis syndrome were significantly higher in the group aged60 than in the group aged≤60(P0.01). The risk of CVD abnormality increased as the scores of Yang-deficiency, blood-stasis and phlegm-damp upgraded. Conclusion CVD test with computer-assisted collision technique is more sensitive than NCV test and can serve as an early and effective index for evaluation of DPN. The course and blood glucose are the independent risk factors for CVD abnormality. Yang-deficiency, blood-stasis and phlegm-damp syndromes have certain effects on the parameters of CVD.

Key concepts: Medicine, Abnormality, Blood stasis, Phlegm, Internal medicine, Diabetes mellitus, Nerve conduction velocity, Gastroenterology

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Analysis on the Conduction Velocity Distribution of Motor Nerve and Characteristic of TCM Syndromes of 148 Patients with Diabetes II — Research Paper | ScholarLens