Correlation between the integron-cassettes and antibiotic multiple resistance in clinical microbes
Hua Chua
Abstract
Hua Chua
Abstract
It was a hard clinical situation of the sensitive bacteria become antibiotic resistance bacteria,especially multi-resistance bacteria.There are so many causations should explain why multiple resistance coming into being,recent study on this subject was integron system both at home and abroad.Integrons are gene capture and expression systems that disseminate resistance gene via plasmids and transposition element.The integron includes a site-specific recombination system capable of integrating and expressing genescontained in structures called gene cassettes.This review was conducted to introduce the structures and functions of integrons and mechanismsthatcontrolintegron-mediatedeventslinkedtomultipleresistance.
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It was a hard clinical situation of the sensitive bacteria become antibiotic resistance bacteria,especially multi-resistance bacteria.There are so many causations should explain why multiple resistance coming into being,recent study on this subject was integron system both at home and abroad.Integrons are gene capture and expression systems that disseminate resistance gene via plasmids and transposition element.The integron includes a site-specific recombination system capable of integrating and expressing genescontained in structures called gene cassettes.This review was conducted to introduce the structures and functions of integrons and mechanismsthatcontrolintegron-mediatedeventslinkedtomultipleresistance.
Key concepts: Integron, Plasmid, Gene cassette, Genetics, Biology, Gene, Antibiotic resistance, Bacteria