The correlation between depression and sex hormone levels of postmenopausal women

Objectives: To explore the correlation between depression and sex hormone levels of postmenopausal women. Methods: Perimenopausal women who took depression self- rating scale in our hospital were chosen and divided into depression group and non- depression group,with 50 patients in each group. 50 women in the childbearing age in the same period were selected as control group. The sex hormone level was detected. Results:In perimenopausal depression group,E2 was( 44. 29 ± 15. 47) pmol / L; FSH was( 18. 91 ± 10. 86) IU / L and LH was( 14. 59 ± 5. 68) IU / L. Comparing with perimenopausal non- depression group,the differences of the above indexes were statistically significant( t = 21. 1929,5. 6134,6. 3077; P 0. 05). Comparing with the normal women in childbearing age,the differences were statistically significant( t = 26. 0704,5. 7674,6. 5832; P 0. 05). In perimenopausal depression group,PRL was( 290. 31 ± 34. 63) pg / m L; P was( 3. 61 ± 2. 07) m IU / m L; T was( 0. 35 ± 0. 31) ng/m L,comparing with perimenopausal non- depression group,there was no statistically significant difference( t = 0. 2583,0. 0955,0. 1639,P 0. 05). There was no statistically significant difference compared with the normal women in childbearing age( t = 0. 5326,0. 1923,0. 3174,P 0. 05). Conclusion: Perimenopausal depression symptoms correlate with the decrease of serum estrogen and increase of follicle- stimulating hormone and luteinizing hormone. The early detection of sex hormone level helps to understand and timely adjust endocrine deficiency of patients. Early diagnosis of perimenopausal depression and evaluation of the degree of depression can improve the living quality of perimenopausal women.