Effects and mechanisms of black soybean anthocyanins on decreasing blood sugar
Wen Han
Abstract
Wen Han
Abstract
Objective: To observe the hypoglycemic effect of Black Soybean Anthocyanins( BSA) and the treatment of diabetes on alloxan-induced artificial diabetic animals.Methods: The different groups of normal mice and the use of modeling alloxan diabetic experimental mice were intraperitoneal injected accordingly concentrations of BSA, and the glucose,superoxide dismutase( SOD) ,malondialdehyde( MDA) ,catalase( CAT) ,glutathione peroxidase ( GSH-PX) were measured as well as insulin levels.Results: The BSA can reduce diabetic mice blood glucose and serum levels of MDA and CAT and increase serum levels of SOD and GSH-PX,while increasing serum levels of insulin.Conclusion: The BSA had the effect of decreasing blood sugar on diabetic mouse induced by alloxan.The mechanism of decreasing blood sugar may be achieved through the promotion of insulin secretion and scavenging free radicals and anti-lipid peroxidation process of implementation.
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Objective: To observe the hypoglycemic effect of Black Soybean Anthocyanins( BSA) and the treatment of diabetes on alloxan-induced artificial diabetic animals.Methods: The different groups of normal mice and the use of modeling alloxan diabetic experimental mice were intraperitoneal injected accordingly concentrations of BSA, and the glucose,superoxide dismutase( SOD) ,malondialdehyde( MDA) ,catalase( CAT) ,glutathione peroxidase ( GSH-PX) were measured as well as insulin levels.Results: The BSA can reduce diabetic mice blood glucose and serum levels of MDA and CAT and increase serum levels of SOD and GSH-PX,while increasing serum levels of insulin.Conclusion: The BSA had the effect of decreasing blood sugar on diabetic mouse induced by alloxan.The mechanism of decreasing blood sugar may be achieved through the promotion of insulin secretion and scavenging free radicals and anti-lipid peroxidation process of implementation.
Key concepts: Alloxan, Malondialdehyde, Chemistry, Superoxide dismutase, Blood sugar, Catalase, Glutathione peroxidase, Insulin