Application of anesthesia with reminfentanil and propofol in craniocerebral operation

Objective To investigate the clinical value of reminfentanil and propofol in craniocerebral operations.Methods Sixty cases of patients in ASA degree Ⅰ-Ⅱ which need endotracheal anesthesia in operating,were randomly divided into two groups : the reminfentanil group(groupⅠ) and the fentanyl group(groupⅡ).Induction of anesthesia was used by intravenous injection with midazolam,vecuronium,propofol and fentanyl,and maintenance of anesthesia was kept by pouring with reminfentanil and propofol in group Ⅰ,but the group Ⅱwas used fentanyl discontinually.Changes of blood pressure,heart rate and anesthesia palinesthesia were observed and recorded continuously during every period of operation.Results compared with the T1,blood pressure and heart rate of the two groups at T2 and T3 were both lower respectively;while cutting scalp and diamonding skull,compared with the groupⅠ,blood pressure and heart rate were increased in groupⅡ.There was no difference about the recovery time,orientation recovery time and extubation time.Conclusion Reminfentanil could be more efficient than fentanyl inendotracheal anesthesia of craniocerebral operations