2010•Zhongguo yaofangRequires access

Efficacy Observation of Fentanyl Transdermal Patches in the Treatment of Cancer Pain

Ping Xu

Abstract

OBJECTIVE:To evaluate the analgesic effects and ADR of fentanyl transdermal patches in different therapies. METHODS:189 patients with cancer pain were randomized into three groups:routine dose fentanyl transdermal patches group(group A) ;routine dose fentanyl transdermal patches +12 h controlled-release morphines(Ms) group(group B) ;twice routine dose fentanyl transdermal patches+12 h controlled-release Ms group(group C) . The curative effects of treatment for 6 days in3 groups were compared by VAS method. RESULTS:In group A,B and C,significant differences were noted in curative efficacy(P0.05 or P0.01) ;There was significant difference between group B and C. there were no significant difference in ADR(P0.05) . CONCLUSION:The therapy of group C shows better analgesic effect,safety and clinical value than the other two groups.

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Available abstract

Key concepts: Transdermal, Fentanyl, Medicine, Analgesic, Anesthesia, Cancer pain, Significant difference, Transdermal patch