2004•Southern China Journal of Dermato-VenereologyRequires access
Investigation on the Efficacy of 0.1% Tazarotene Gel in Treatment of Patients with Acne Vulgaris
Zhihua Wu
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Abstract
Objective:To observe the clinical efficacy and safety of 0.1% tazarotene gel short-contact therapy adopted in treatment of mild or moderate facial acne. Methods:A randomized, parallel controlled clinical study was conducted. The patients were treated topically with trial drug, twice-daily (morning and evening) for 12 weeks. Results:Results showed that the effective rates were 24%,40%,60% and 68% respectively in study group at 2,4,8 and 12 weeks. In control group, the effective rates were 19.2% (P=0.631, compared to the study group), 23.1% (P=0.175), 30.8% (P=0.034) and 30.8% (P=0.008) respectively. Conclusion:Short-contact treatment of 0.1% tazarotene gel for mild to moderate facial acne was effective, safe and well tolerated.