2001•Chinese journal of integrated traditional and Western medicineRequires access
Effect of Acupuncture and Moxibustion on Memory Function and Cortical Cholinergic System in Dementia Mimetic Rats
Li Ding
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Abstract
Objective:To study the effect of acupuncture and moxibustion on memory function and cortical cholinergic system in dementia mimetic rats.Methods:Dementia mimetic rat model was established with aluminum chloride solution subcutaneously given.The effect of acupuncture on cholinergic M-receptor bonding capacity and cholinesterase activity in cerebral cortex of rats were determined by using Morris maze test and compared among model,acupuncture,moxibustion and control groups.Results:Acupuncture and moxibustion could significantly improve memory of the dementia mimetic rats model,and there existed no obvious difference between acupuncture and moxibustion,it could also increase the M-receptor binding capacity and reduce the activity of cholinesterase in model rats.Conclusion: Acupuncture and moxibustion could improve memory and are helpful in the prevention and treatment of brain dysfunction.